This is in contrast to today's more common concurrency model, in which OS threads are employed. Thread-based networking is relatively inefficient and very difficult to use. Furthermore, users of Node.js are free from worries of dead-locking the process, since there are no locks. Almost no function in Node.js directly performs I/O, so the process never blocks except when the I/O is performed using synchronous methods of Node.js standard library. Because nothing blocks, scalable systems are very reasonable to develop in Node.js.
If some of this language is unfamiliar, there is a full article on Blocking vs. Non-Blocking.